Dr. Marie-Laure JOURDAIN / MCU-PH
Tél : +33 3 26 91 34 55
Email : marie-laure.jourdain@univ-reims.fr
♦ Parodontologie
♦ Société Française de Parodontologie et Implantologie Orale (SFPIO)
♦ Collège National des Enseignants en Parodontologie (CNEP)
Equipe d’Accueil EA 4691 "BIOS":
Biomatériaux et Inflammation en Site Osseux.
♦ Etude clinique pilote (PAROPAM): Dosage de l’expression des gènes codant les peptides antimicrobiens chez les patients atteints de parodontite chronique généralisée modérée à sévère.
Effet de la mutation du gène CFTR sur la physiologie osseuse : implication de la sphingosine 1 phosphate dans la communication cellulaire ostéoblastes/ostéoclastes dans le cadre de la maladie osseuse liée à la mucoviscidose
♦ Velard F*, Jourdain ML*, Abdallah D, Jacquot J, Ronan N, McCarthy Y, Flanagan E, Plant B. Overexpression of RANK and M-CSFR in Monocytes of G551D-Bearing Patients with Cystic Fibrosis. Am J Respir Crit Care Med. 2018 Oct 1;198(7):968-970. doi: 10.1164/rccm.201803-0415LE. PMID: 29940131.
♦ Jourdain ML, Pierrard L, Kanagaratnam L, Velard F, Sergheraert J, Lefèvre B, Gangloff SC, Braux J. Antimicrobial peptide gene expression in periodontitis patients: A pilot study. J Clin Periodontol. 2018 May;45(5):524-537. doi: 10.1111/jcpe.12879. Epub 2018 Mar 23. PMID: 29446150.
♦ Jourdain ML, Velard F, Pierrard L, Sergheraert J, Gangloff SC, Braux J. Cationic antimicrobial peptides and periodontal physiopathology: A systematic review. J Periodontal Res. 2019 Dec;54(6):589-600. doi: 10.1111/jre.12676. Epub 2019 Jun 19. PMID: 31215656.
♦ Braux J, Jourdain ML, Guillaume C, Untereiner V, Piot O, Baehr A, Klymiuk N, Winter N, Berri M, Buzoni-Gatel D, Caballero I, Guillon A, Si-Tahar M, Jacquot J, Velard F. CFTR-deficient pigs display alterations of bone microarchitecture and composition at birth. J Cyst Fibros. 2020 May;19(3):466-475. doi: 10.1016/j.jcf.2019.10.023. Epub 2019 Nov 29. PMID: 31787573.v
♦ Abdallah D*, Jourdain ML*, Braux J, Guillaume C, Gangloff SC, Jacquot J, Velard F. An Optimized Method to Generate Human Active Osteoclasts From Peripheral Blood Monocytes. Front Immunol. 2018 Apr 4;9:632. doi: 10.3389/fimmu.2018.00632. PMID: 29670619; PMCID: PMC5893639.
♦ Jourdain ML, Sergheraert J, Braux J, Guillaume C, Gangloff SC, Hubert D, Velard F, Jacquot J. Osteoclastogenesis and sphingosine-1-phosphate secretion from human osteoclast precursor monocytes are modulated by the cystic fibrosis transmembrane conductance regulator. Biochim Biophys Acta Mol Basis Dis. 2021 Mar 1;1867(3):166010. doi: 10.1016/j.bbadis.2020.166010. Epub 2020 Nov 11. PMID: 33188942.
♦ Delion M, Braux J, Jourdain ML, Guillaume C, Bour C, Gangloff S, Pimpec-Barthes FL, Sermet-Gaudelus I, Jacquot J, Velard F. Overexpression of RANKL in osteoblasts: a possible mechanism of susceptibility to bone disease in cystic fibrosis. J Pathol. 2016 Sep;240(1):50-60. doi: 10.1002/path.4753. PMID: 27235726.
♦ Braux J, Velard F, Guillaume C, Jourdain ML, Gangloff SC, Jallot E, Nedelec JM, Laquerrière P, Laurent-Maquin D. Strontium-Substituted Bioceramics Particles: A New Way to Modulate MCP-1 and Gro-α Production by Human Primary Osteoblastic Cells. Materials (Basel). 2016 Dec 5;9(12):985. doi: 10.3390/ma9120985. PMID: 28774105; PMCID: PMC5456992.