Inducing plant resistance to pathogens using Beneficial microorganisms (BMO) or their derivatives is a promising strategy for sustainable agriculture. It is partly based on activation of plant immune responses. These methods are efficient to control several fungal-associated diseases but the mechanisms involved are not fully understood. Our researches aim at identifying molecular, biochemical and cellular events involved in BMO-induced resistance towards plant pathogens. Our study encompass several fungal diseases (downy mildew, grey rot and botryospheria dieback) on several plant models (thale crest, tomato, rapeseed and grapevine).