Contact details

Associate Professor at the University of Reims Champagne-Ardenne

Faculty of Exact and Natural Sciences
Institute of Molecular Chemistry – ICMR UMR CNRS 7312
Group « Methodology and Organic Synthesis
BP 1039
51687 Reims Cedex 2
Phone : 00 33 3.26.91.31.64
E-Mail : fabienne.grellepois@univ-reims.fr

Website : ICMR

Key words

Organic synthesis; methodology; fine chemicals

Main publications

- The role of the counterion and of silicon chelation in the selective mono(trifluoromethylation) of tartaric acid-derived 1,4-diketones.
D. Harakat, F. Massicot, J. Nonnenmacher, F. Grellepois, C. Portella Chem. Eur. J. 2011, 17 (38), 10636-10642.

- Enantiomerically pure 2-aryl(alkyl)-2-trifluoromethylaziridines: Synthesis and ring opening with selected O- and N-nucleophiles.
F. Grellepois, J. Nonnenmacher, F. Lachaud, C.Portella Org. Biomol. Chem. 2011, 9 (4), 1160-1168.

- Enantiopure 2-trifluoromethyl-1,2,3,4-tetrahydronaphthalen-1,2-diols from tartaric acid-derived scaffold.
F. Massicot, J. Nonnenmacher, F. Grellepois, C. Portella Eur. J. Org. Chem.2010, 275-279.

S- ynthesis of enantiopure 2-aryl(alkyl)-2-trifluoromethyl-substituted morpholines and oxazepanes.
J. Nonnenmacher, F. Grellepois, C. Portella Eur. J. Org. Chem. 2009, 3726-3731

- Synthesis of enantiopure quaternary a-trifluoromethyl-a-alkoxyaldehyde from L-tartaric acid-derived ketoamides.
J. Nonnenmacher, F. Massicot, F. Grellepois, C. Portella J. Org. Chem. 2008, 73, 7990-7995.