HAUDRECHY Arnaud

arnaud

Fonction


Professeur des universités, Université de Reims Champagne-Ardenne

Coordonnées


U.F.R. SCIENCES EXACTES ET NATURELLES

Campus du Moulin de La Housse BP 1039 51687 REIMS Cedex 2
Tél. 03.26.91.32.36
Mèl : arnaud.haudrechy@univ-reims.fr

Activités de recherche


Sucres et synthèse totale

Mots-clefs


Sucres ; synthèse totale

Enseignement


Licence 1ère année, PACES et Master 1ère et 2ème année

Programmes nationaux et internationaux


Création du Glycolipid European Network (GLEN)

Conférences internationales


1- Synthèse Totale de l’Huperzine A, SECO, le 25/5/00 à Houffalize
2- Sur la Route de la Fumagilline, le 22/4/03 à Montréal (UQAM)
3- On the Road to Fumagillin, le 23/4/03 à Montréal (Concordia University)
4- Two stimulating concepts in natural substances synthesis: the NEO cascade and the CIM strategy, 30 juin au 2 juillet 2010, International Conference on Medicinal Chemistry, Reims.
5- A stimulating concept in natural substances synthesis: the CIM strategy, 23 novembre 2011, Queen’s University, Belfast.

6- An efficient synthetic approach to natural products: the Claisen-Ireland/Metathesis strategy, 5 Octobre 2015, 1st Meeting of COST Action CM1407, Sapienza University, Roma.

Publications principales


1- Cyclization of Hydroxy Enol Ethers : A Stereocontrolled Approach To 3-deoxy-D-Manno-2-octulosonic Acid containing Disaccharides, A. Haudrechy and P. Sinaÿ*, J. Org. Chem., 1992, 57, 4142

2- Preferred Conformations of C-Glycosides, 14. Synthesis and Conformational Analysis of Carbon Analogs of the Blood Group Determinant H-Type II, A. Wei, A. Haudrechy, C. Audin, H.-S. Jun, N. Haudrechy-Bretel and Y. Kishi*, J. Org. Chem., 1995, 60, 2160

3- Analysis of the Diastereoselectivity of a Diels-Alder Cycloaddition through 2H NMR in chiral liquid crystals, A. Meddour, A. Haudrechy, P. Berdagué, W. Picoul, Y. Langlois and J. Courtieu, Tetrahedron: Asymmetry, 1996, 7, 2489

4- A Simple Method of Drawing Stereoisomers From Complicated Symmetrical Structures, A. Haudrechy, J. Chem. Ed., 2000, 864

5- A Formal Synthesis of (+)-Huperzin A, C. Chassaing, A. Haudrechy, C. Riche and Y. Langlois*, Tetrahedron, 2000, 56, 3181

6- A Stereoselective Formal Synthesis of Fumagillin, O. Bedel, A. Haudrechy*, Y. Langlois*, Eur. J. Org. Chem., 2004, 3813

7- Highly Enantioselective Sequential Claisen-Ireland / Metathesis: Synthesis of Cycloalkenes Bearing two Contiguous Highly Functionalized Asymmetric Centers, A. Français, O. Bedel,
W. Picoul, A. Meddour, J. Courtieu and A. Haudrechy*, Tetrahedron Asymmetry, 2005, 16, 1141

8- Diastereoselective Access to the Spirotetronate Subunit of the Quartromicins, O. Bedel*, A. Français and A. Haudrechy*, Synlett, 2005, 15, 2313

9- Selective Synthesis of a-C-(alkynyl)-Galactosides by an Efficient Tandem Reaction, S. Guillarme, K. Plé and A. Haudrechy*, J. Org. Chem., 2006, 71, 3, 1015

10- Alkynylation of Chiral Aldehydes: Alkoxy-, Amino- and Thioaldehydes, S. Guillarme, K. Plé*, A. Banchet, A. Liard and A. Haudrechy*, Chem. Reviews, 2006, 106(6); 2355

11-Quiral: a Computer Program for the Synthesis of Chiral Molecules from Sugars, J.-M. Nuzillard and A. Haudrechy, Tetrahedron Letters, 2007, 48, 13, 2311-2313

12- Is Osmylation Always Preferring the Richest Double Bond?, A. Français, O. Bedel, A. Haudrechy*, Tetrahedron, 2008, 2495

13- Molecular Dynamics Simulation Study on the Interaction of KRN 7000 and three analogues with Human CD1d, E. Hénon*, M. Dauchez, A. Haudrechy, A. Banchet, Tetrahedron, 2008, 9480

14- D-C-Mannopyranosides, M. Choumane, A. Banchet, N. Probst, S. Gérard, K. Plé*, A. Haudrechy*, Comptes Rendus de Chimie, 2011, 14, 2-3, 235

15- The stimulating adventure of KRN 7000, A. Banchet-Cadeddu, E. Hénon, M. Dauchez,J.-H. Renault, F. Monneaux,A. Haudrechy, Org. Biomol. Chem., 2011, 9, 3080

16- The Chemistry of L-Sorbose, I. Zebiri, S. Balieu, A. Guilleret, R. Reynaud, A. Haudrechy, Eur. J. Org. Chem., 2011, 16, 2905

17- A further contribution to the study of Sagittamide A: Synthesis of a pivotal intermediate belonging to a rare L-series, A. Humbert, K. Plé, D. Harakat, A. Martinez, A. Haudrechy, Molecules, 2012, 17, 7, 7709-7721

18- Stereoselective synthesis of (2S,3S,4R,5S)-2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine derivatives from L-Sorbose, S. Balieu, A. Guilleret, R. Reynaud, A. Haudrechy, Carb. Res., 2013, 374, 14-22

19- Are the furanosides that flexible? A Ring Dihedral Principal Component Analysis of furanose conformation, C. Coiffier, C. Barberot, J.-M. Nuzillard, P. Goekjian, E. Hénon, A.Haudrechy, Carbohydrate Chem., 2014, 40, 378-400.

20- From D-Xylose to a D-Glycero-L-altrose derivative, A. Banchet-Cadeddu, A. Haudrechy, Tetrahedron Lett. 2014, 55, 4605-4607.

21- Stereocontrolled Synthesis of Hydrophobic Moiety of Rhamnolipids Derivatives, B. Menhour, P. Mayon, K. Plé, S. Bouquillon, S. Dorey, C. Clément, M. Deleu, A. Haudrechy, Tetrahedron Lett. 2015, 56, 1159-1161

22- Interactions of Sugar-Based Bolaamphiphiles with Biomimetic Systems of Plasma Membranes, M. N. Nasir, J.-M. Crowet, L. Lins, F. Obounou-Akong, A. Haudrechy, S. Bouquillon, M. Deleu, Biochimie 2016, 130, 23-32

23- Recycling Mitsunobu Coupling : a Shortcut for Troublesome Esterifications, B. Menhour, F. Obounou Akong, P. Mayon, K. Plé, S. Bouquillon, S. Dorey, C. Clément, M. Deleu, D. Harakat, A. Haudrechy, Tetrahedron 2016, 72, 7488-7495

24- Differential Interaction of Synthetic Glycolipids with Biomimetic Plasma Membrane Lipids correlates with Plant Biological Response, M. N. Nasir, L. Lins, J.-M. Crowet, M. Ongena, S. Dorey, S. Dhondt-Cordelier, C. Clément, S. Bouquillon, A. Haudrechy, C. Sarazin, M.-L. Fauconnier, K. Nott, M. Deleu, Langmuir 2017, 26, 9979-9987

Prix, récompenses


Prix Dina Surdin 91 (prix national de thèse de la Division de Chimie Organique de la Société Française de Chimie)