Research Axis 2 - Methodologies

- Tumor Growth (xenograft, syngenic model).

- Cell invasion and migration (modified Boyden chambers, artificial wound, spontaneous migration, videomicroscopy, confocal microscopy, 3D-reconstruction).

- Angiogenesis and lymphangiogenesis (in vitro et in vivo assays, immunostaining, Raman spectroscopy).

- Spectroscopic signatures of the extracellular matrix macromolecules (Raman and Infrared microspectroscopies).

- Receptors and signaling studies.

- Determination of minimal active sequence and molecular dynamic simulations.

- Development of anticancer agents derived from matrikines.