Research Axis 2 - Methodologies
- Tumor Growth (xenograft, syngenic model).
- Cell invasion and migration (modified Boyden chambers, artificial wound, spontaneous migration, videomicroscopy, confocal microscopy, 3D-reconstruction).
- Angiogenesis and lymphangiogenesis (in vitro et in vivo assays, immunostaining, Raman spectroscopy).
- Spectroscopic signatures of the extracellular matrix macromolecules (Raman and Infrared microspectroscopies).
- Receptors and signaling studies.
- Determination of minimal active sequence and molecular dynamic simulations.
- Development of anticancer agents derived from matrikines.